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達(dá)旦黃號：1829-00-1   
英文名稱：Titan yellow；Chlorazol yellow2G；Diazamine golden yellow T；Clayton yellow；Thiazol(e) yellow；Thiazol yellow G；2,2′-[( Diazoamino)-di-p-phenylene]-bis-(6-methyl-7-benzothiazole sulfonic acid disodium salt；Direct yellow 9；C.I. 19540   
其他名稱：2,2’-(1-三嗪-1,3-二基二-4,1-亞苯基)雙(6-甲基-7-苯并噻唑磺酸)二鈉鹽；噻唑黃；鈦黃；鎳鈦黃；蒂坦黃   
號：1829-00-1   
C28H19N5Na2O6S4=695.72   
級別：IND   
含量：≥65%   
pH變色域：11.0（黃色）～13.0（紅色）   
溶解度試驗：合格   
干燥失量：≤10.0%   
性狀(以下信息僅供參考)：淺黃棕色粉末。對光敏感。溶于水、乙醇(呈黃色溶液)、氫氧化鈉溶液(呈紅黃色)、硫酸(呈棕黃色)。Z大吸收波長 402nm   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)光度測定鎂。檢定硼和鎂。酸堿指示劑，pH11.0(黃)～13.0(紅)。生物染色劑。顯微鏡檢查法用熒光指示劑。吸附指示劑   
保存：RT，避光。保質(zhì)期5年  客戶根據(jù)達(dá)旦黃號：1829-00-1性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況，本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定，運輸條件不苛刻，一般儲存在陰涼，干燥，通風(fēng)良好的地方，遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
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form is termed pp60c-src. Dephosphorylated by PTPRJ at Tyr-419. Normally maintained in an inactive conformation with the SH2 domain engaged with Tyr-530, the SH3 domain engaged with the SH2-kinase linker, and Tyr-419 dephosphorylated. Dephosphorylation of Tyr-530 as a result of protein tyrosine phosphatase (PTP) action disrupts the intramolecular interaction between the SH2 domain and Tyr-530, Tyr-419 can then become autophosphorylated, resulting in SRC activation. Phosphorylation of Tyr-530 by CSK allows this interaction to reform, resulting in SRC inactivation. CDK5-mediated phosphorylation at Ser-75 targets SRC to ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. Phosphorylated by PTK2/FAK1; this enhances kinase activity. Phosphorylated by PTK2B/PYK2; this enhances kinase activity.
S-nitrosylation is important for activation of its kinase activity (By similarity).
Ubiquitinated in response to CDK5-mediated phosphorylation.
DISEASE : Note=SRC kinase activity has been shown to be increased in several tumor tissues and tumor cell lines such as colon carcinoma cells.
Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: P12931.3
英文名稱  Anti-SCP2/NLTP
中文名稱  固醇攜帶蛋白2抗體
別    名  DKFZp686C12188; DKFZp686D11188; NLTP; Nonspecific lipid transfer protein; NSL TP; OTTHUMP00000010488; Propanoyl CoA C acyltransferase; SCP 2; SCP chi; SCP X; SCP2; SCPchi; SCPX; Sterol carrier protein 2; Sterol carrier protein X; NLTP_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Cow, Rabbit
產(chǎn)品類型  一抗   
研究領(lǐng)域  心血管 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號 細(xì)胞周期蛋白 合成與降解 細(xì)胞分化 細(xì)胞骨架 線粒體 
蛋白分子量  predicted molecular weight: 59kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human SCP2 C-terminus
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 This gene encodes two proteins: sterol carrier protein X(SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]
Function : Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
Subunit : Interacts with PEX5.
Subcellular Location : Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues.
Isoform SCPx: Peroxisome. Note=Interaction with PEX5 is essential for peroxisomal import.
Isoform SCP2: Mitochondrion (Probable).
Tissue Specificity : Liver, fibroblasts, and placenta.