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半二甲酚橙號(hào)：19329-67-0   
英文名稱：Semixylenol Orange；N-(Carboxymethyl)-N-((2-hydroxy-5-(3-(4-hydroxy-3-methylphenyl)-3H-2,1-benzoxathiol-3-yl)-3-methylphenyl)methyl)glycine S；S-dioxide   
其他名稱：半二甲酚桔黃；3-[N,N-二(羧甲基)氨甲基]鄰甲酚磺酞   
號(hào)：19329-67-0   
C24H23NNa2O9S=547.49   
級(jí)別：AR   
水溶解試驗(yàn)：合格   
對(duì)鉍靈敏度試驗(yàn)：合格   
灼燒殘?jiān)? ≤25.0%   
性狀(以下信息僅供參考)：橙紅色粉末。能與多種金屬離子絡(luò)合,其溶液為紅紫色。溶于水,不溶于無水乙醇   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)滴定鐵、鋁、鉛和釷的絡(luò)合指示劑。光度測(cè)定鉍、鋯、鉿和釷   
保存：RT。保質(zhì)期5年 客戶根據(jù)半二甲酚橙號(hào)：19329-67-0性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱、純度、級(jí)別等情況，本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定，運(yùn)輸條件不苛刻，一般儲(chǔ)存在陰涼，干燥，通風(fēng)良好的地方，遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
試劑品牌：TCI、sigma、Alfa、Avocado、Aldrich、ACROS、Fluka、ICN（MP）等
包裝：1kg、100g、10g、250g、25g、500g、50g、5g等包裝
級(jí)別：GR級(jí)別、AR級(jí)別、CP級(jí)別、L.P.級(jí)別等
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Similarity : In the N-terminal section; belongs to the thiolase family.
Contains 1 SCP2 domain.
Database links : UniProtKB/Swiss-Prot: P22307.2
固醇攜帶蛋白2(SCP2)參與了*的合成、代謝和轉(zhuǎn)運(yùn)過程.與膽囊固醇結(jié)石形成有關(guān).
英文名稱  Anti-SLC4A4
中文名稱  *協(xié)同轉(zhuǎn)運(yùn)蛋白4-A4抗體
別    名  DKFZp781H1314; Electrogenic sodium bicarbonate cotransporter 1; hhNMC; HNBC 1; HNBC1; kNBC 1; KNBC; kNBC1; Na(+)/HCO3(-) cotransporter; Na+HCO3- cotransporter 4; NBC 1; NBC 2; NBC1; NBC2; Nbc4; NBCE 1; NBCE1; PNBC; SLC4A5; Sodium bicarbonate cotransporter kidney; sodium bicarbonate cotransporter member 4; Sodium bicarbonate cotransporter pancreas; Solute carrier family 4 member 4; solute carrier family 4 sodium bicarbonate cotransporter member 4; Solute carrier family 4 sodium bicarbonate cotransporter member 5.
濃    度  1mg/1ml
規(guī) 格  0.1ml/100μg  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep
產(chǎn)品類型  一抗   
研究領(lǐng)域 
蛋白分子量  predicted molecular weight: 119kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human SLC4A4
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 半二甲酚橙號(hào)：19329-67-0optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 SLC4A4 (Electrogenic sodium bicarbonate cotransporter 1) is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. It may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. SLC4A4 interacts with carbonic anhydrase 2 and carbonic anhydrase 4 which may regulate transporter activity. There are four named isoforms produced by alternative splicing.
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
Function : Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.
Subunit : Interacts with CA2/carbonic anhydrase 2 and CA4/carbonic anhydrase 4 which may regulate transporter activity.
Subcellular Location : Basolateral cell membrane; Multi-pass membrane protein.
Tissue Specificity : Isoform 1 is expressed in pancreas and to a lower extent in heart, skeletal muscle, liver, parotid salivary glands, prostate, colon, stomach, thyroid, brain and spinal chord. Corneal endothelium cells express only isoform 1 (at protein level). Isoform 2 is specifically expressed in kidney at the level of proximal tubules.
Post-translational modifications : Phosphorylation of Ser-1026 by PKA increases the binding of CA2 and changes the Na(+):HCO3(-) stoichiometry of the transporter from 3:1 to 2:1. Phosphorylation of Thr-49 regulates isoform 1 conductance.
N-glycosylation is not necessary for the transporter basic functions.