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聯(lián)系我時,請告知來自 儀表網(wǎng)N-(4-氨基丁基)-N-乙基異魯米諾號:66612-29-1
3,3'5,5'-四甲基聯(lián)苯胺丙磺酸鈉號:102062-36-2
N-乙基-N-(3-磺丙基)-3-甲氧基苯胺鈉鹽號:82611-88-
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鈣指示劑號:3737-95-9
英文名稱:Calconcarboxylic acid;3-Hydroxy-4-(2-hydroxy-4-sulfo-1-naphthylazo)naphthalene-2-carboxylic acid
其他名稱:鈣羧酸指示劑;鈣紅;鈣羧酸鈉;鈣羧酸;鈣試劑羧酸鈉;3-羥基-4-[(2-羥基-4-磺基-1-萘基)偶氮]-2-萘羧酸;2-羥基-1-(2-羥基-4-磺基-1-萘基偶氮)-3-萘甲酸;鈣試劑羧酸;3-羥基-4-(2-羥基-4-磺基-1-萘基偶氮)萘-2-羧酸;1-(2-羥基-4-磺基-1-萘基偶氮)-2-羥基-3-萘甲酸
號:3737-95-9
C21H14N2O7S=438.41
級別:IND
稀氫氧化鈉溶液溶解試驗:合格
絡合試驗:合格
滴定試驗:合格
灼燒殘渣(以硫酸鹽計):≤0.3%
性狀(以下信息僅供參考):棕色至黑色結晶或褐色粉末。易溶于堿液和氨水,微溶于水。在pH不大于10時呈紅色,pH13~14間為淺藍色,能和鈣形成紅色螯合物。熔點300℃。Z大吸收波長 560(366)nm。有刺激性。商品也有制成鈉鹽的,易溶于水,水溶液和乙醇溶液均不穩(wěn)定。常與100倍的化鈉混勻后使用
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)絡合指示劑,測定鈣
保存:RT 客戶根據(jù)鈣指示劑號:3737-95-9性質、化學式、分子式、結構式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況,本產(chǎn)品化學性質穩(wěn)定,運輸條件不苛刻,一般儲存在陰涼,干燥,通風良好的地方,遠離不相容的物質。保持容器密閉。
試劑品牌:TCI、sigma、Alfa、Avocado、Aldrich、ACROS、Fluka、ICN(MP)等
包裝:1kg、100g、10g、250g、25g、500g、50g、5g等包裝
級別:GR級別、AR級別、CP級別、L.P.級別等
公司提供的鈣指示劑號:3737-95-9*,貨源充足。嚴格的生產(chǎn)質量控制體系,包括:優(yōu)級純,分析純,化學純,試劑級,基準試劑,實驗純,教學試劑,高純試劑,色譜純,光譜純,電子純。各種包裝規(guī)格,并可提供包裝定制,咨詢訂購。
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產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, plaet aggregation, and cardiac myocyte function.
Function : Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of plaets.
Isoform e3C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Subunit : Homodimer. Interacts with NOSIP and NOSTRIN.
Subcellular Location : Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Tissue Specificity : Plaets, placenta, liver and kidney.
Post-translational modifications : Phosphorylation by AMPK at Ser-1177 in the presence of Ca(2+)-calmodulin (CaM) activates activity. In absence of Ca(2+)-calmodulin, AMPK also phosphorylates Thr-鈣指示劑號:3737-95-9495, resulting in inhibition of activity. Phosphorylation of Ser-114 by CDK5 reduces activity.
Similarity : Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Database links : UniProtKB/Swiss-Prot: P29474.3 human
UniProtKB/Swiss-Prot: Q62600.4 rat
UniProtKB/Swiss-Prot: P70313.4 mouse
英文名稱 Anti-Phospho-eNOS (Ser116)
中文名稱 磷酸化一氧化氮合成酶3(內(nèi)皮型)抗體
別 名 eNOS (phospho S116); p-eNOS (phospho S116); eNOS (Phospho-Ser116); cNOS; eNOS; Constitutive NOS; EC NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; Nitric oxide synthase 3 (endothelial cell); Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; nitric oxide synthase, endothelial; NOS 3; NOS III; NOS type III; NOS3; NOSIII; NOS3_HUMAN.
濃 度 1mg/1ml
規(guī) 格 0.1ml/100μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Pig, Cow, Sheep
產(chǎn)品類型 一抗 磷酸化抗體
研究領域 腫瘤 細胞生物 神經(jīng)生物學 信號轉導 激酶和磷酸酶 合成與降解 新陳代謝
蛋白分子量 predicted molecular weight: 133kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat eNOS around the phosphorylation site of Ser116
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic
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