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鉍試劑Ⅰ號(hào)：1072-71-5   
英文名稱：DMTD ；Bismuththiol Ⅰ；,3,4-Thiadiazole-2,5-dithiol；2,5-Dimercapto-1,3,4-thiadiazole   
其他名稱：2,5-二巰基-1,3，4-硫代二氮唑；二硫醇硫代二氮唑；二巰基噻二唑；2,5-二巰基噻二唑；二硫基硫代二唑；2,5-二巰基-1-硫-3,4-二氮茂；1,3,4-噻唑烷-2,5-二硫酮；2,5-二巰基-1,3,4噻二唑   
號(hào)：1072-71-5   
C2H2N2S3=150.25   
級(jí)別：BR   
含量：≥98.0%   
性狀(以下信息僅供參考)：黃色針狀結(jié)晶或粉末。易溶于乙迷和堿溶液，微溶于乙醇，不溶于水、方和苯。堿性溶液不穩(wěn)定，久置有硫析出。有刺激性。   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)檢定鉍、銅、鉛、鈀和銻。光度測定鉍和鈀。鉍的容量測定   
保存：RT，避光。保質(zhì)期5年 客戶根據(jù)鉍試劑Ⅰ號(hào)：1072-71-5性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱、純度、級(jí)別等情況，本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定，運(yùn)輸條件不苛刻，一般儲(chǔ)存在陰涼，干燥，通風(fēng)良好的地方，遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
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applications.
產(chǎn)品介紹 eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, plaet aggregation, and cardiac myocyte function.
Function : Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of plaets.
Isoform e3C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Subunit : Homodimer. Interacts with NOSIP and NOSTRIN.
鉍試劑Ⅰ號(hào)：1072-71-5Subcellular Location : Cell membrane. Membrane > caveola. Cytoplasm > cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle and which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Tissue Specificity : Plaets, placenta, liver and kidney.
Post-translational modifications : Phosphorylation by AMPK at Ser-1177 in the presence of Ca(2+)-calmodulin (CaM) activates activity. In absence of Ca(2+)-calmodulin, AMPK also phosphorylates Thr-495, resulting in inhibition of activity. Phosphorylation of Ser-114 by CDK5 reduces activity.
Similarity : Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
Database links : UniProtKB/Swiss-Prot: P29474.3 human
UniProtKB/Swiss-Prot: Q62600.4 rat
UniProtKB/Swiss-Prot: P70313.4 mouse
催化生物體內(nèi)一氧化氮（NO）生成的酶。分神經(jīng)型一氧化氮合成的酶（nNOS or NOS-1）、誘導(dǎo)型一氧化氮合成的酶（iNOS or NOS-2）、內(nèi)皮型一氧化氮合成的酶（eNOS or NOS-3）。此抗體識(shí)別分子量為135kDa的內(nèi)皮型一氧化氮合成的酶。
英文名稱  Anti-Phospho-eNOS (Ser615)
中文名稱  磷酸化一氧化氮合成酶3（內(nèi)皮型）抗體
別    名  eNOS (phospho S615); p-eNOS (phospho S615); eNOS (Phospho-Ser615); cNOS; eNOS; Constitutive NOS; EC NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; Nitric oxide synthase 3 (endothelial cell); Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; nitric oxide synthase, endothelial; NOS 3; NOS III; NOS type III; NOS3; NOSIII; NOS3_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.1ml/100μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep
產(chǎn)品類型  一抗  磷酸化抗體  
研究領(lǐng)域  腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 合成與降解 新陳代謝 
蛋白分子量  predicted molecular weight: 133kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated Synthesised phosphopeptide derived from human eNOS around the phosphorylation site of Ser615
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including