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偶氮膦Ⅲ 號(hào):1914-99-4

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偶氮膦Ⅲ 號(hào):1914-99-4穩(wěn)定性強(qiáng)、梯度性好、超越ACS標(biāo)準(zhǔn)、低水分、低蒸發(fā)殘?jiān)V泛應(yīng)用于教學(xué)、科學(xué)研究、分析測(cè)試中,是進(jìn)行化學(xué)實(shí)驗(yàn)、材料分析和精細(xì)化學(xué)品合成所必須的,保證不同批次產(chǎn)品的質(zhì)量穩(wěn)定低紫外吸收背景。

偶氮膦Ⅲ 號(hào):1914-99-4  
英文名稱:CPA-Ⅲ;Chlorophosphonazo Ⅲ;3,6-Bis[(4-chloro-2-phosphonophenyl)azo]-4,5-dihydroxynaphthalene-2,7-disulphonic acid    
其他名稱:偶氮磷Ⅲ;2,7-雙(4--2-膦羧苯偶氮)-1,8-二羥基萘-3,6-二磺酸;膦酸偶氮III   
號(hào):1914-99-4    
C22H16Cl2N4O14P2S2?4H2O=801.33   
級(jí)別:顯色劑   
對(duì)稀土金屬靈敏度試驗(yàn):合格   
水溶解試驗(yàn):合格   
性狀(以下信息僅供參考):紫褐色結(jié)晶性粉末。易溶于水,微溶于乙醇和丙同,不溶于乙迷、苯、方。在pH<3的水溶液中呈玫瑰紅色,pH=3的水溶液中呈玫瑰紅色略帶紫色,pH>4時(shí)轉(zhuǎn)為紫色。在濃硫酸中呈淺綠色。在濃硝酸中分解。在氫氧化鈉和碳酸鈉溶液中呈淺藍(lán)色。摩爾吸光系數(shù)為74,500~75,500,具有比偶氮胂Ⅰ更高的絡(luò)合性能。   
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)分光光度測(cè)定鈾和鈣??稍诓煌瑮l件下與鈣、鋇、鎂、銅、鋅、鉛、鐵、鈷、鎳、鈹、鋁、釔、釷、鈰和銨等形成有色絡(luò)合物   
保存:RT 偶氮膦Ⅲ 號(hào):1914-99-4儲(chǔ)存條件:
避光、干燥陰涼處封閉貯存,嚴(yán)禁與有毒、有害物品混放、混運(yùn)。本品為非危險(xiǎn) 產(chǎn)品可按一般化學(xué)品運(yùn)輸,輕搬動(dòng)輕放,防止日曬、雨淋!受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運(yùn)輸條件比較苛刻。
運(yùn)輸:汽車運(yùn)輸、EMS郵政快遞,申通快遞等, 款到上海3天內(nèi)發(fā)貨;
售后:如您對(duì)我們的產(chǎn)品服務(wù)及技術(shù)指標(biāo)有特殊要求,請(qǐng)及時(shí)通知我方。
存儲(chǔ):應(yīng)貯存在干燥清潔避光的環(huán)境中,嚴(yán)禁與有毒物質(zhì)混放,以免污染(保質(zhì)期為兩年)。
偶氮膦Ⅲ 號(hào):1914-99-4主要優(yōu)級(jí)純、分級(jí)純和化學(xué)純3種:
(1)優(yōu)級(jí)純(GR:Guaranteed reagent),又稱一級(jí)品或保證試劑,99.8%,這種試劑純度Z高,雜質(zhì)含量Z低,適合于重要精密的分析工作和科學(xué)研究工作,使用綠色瓶簽。
(2)分析純(AR),又稱二級(jí)試劑,純度很高,99.7%,略次于優(yōu)級(jí)純,適合于重要分析及一般研究工作,使用紅色瓶簽。
(3)化學(xué)純(CP),又稱三級(jí)試劑,≥ 99.5%,純度與分析純相差較大,適用于工礦、學(xué)校一般分析工作。使用藍(lán)色(深藍(lán)色)標(biāo)簽。
(4)實(shí)驗(yàn)試劑(LR:Laboratory reagent),又稱四級(jí)試劑。
服務(wù)承諾:
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Subunit : Component of the MRN complex composed of two heterodimers RAD50/MRE11A associated with a single NBN. Component of the BASC complex, at least composed of BRCA1, MSH2, MSH6, MLH1, ATM, BLM, RAD50 and MRE11A (By similarity). Interacts with histone H2AFX this requires phosphorylation of H2AFX on 'Ser-139'. Interacts with HJURP, INTS3, KPNA2 and TERF2. Interacts with RBBP8; the interaction links the role of the MRN complex in DNA double-strand break sensing to resection. Interacts with SP100; recruits NBN to PML bodies.
Subcellular Location : Nucleus (By similarity). Nucleus, PML body. Chromosome, omere (By similarity). Note=Localizes to discrete nuclear foci after treatment with genotoxic agents (By similarity).
Tissue Specificity : Ubiquitous. Expressed at high levels in testis.
Post-translational modifications : Phosphorylated by ATM in response of ionizing radiation, and such phosphorylation is responsible intra-S phase checkpoint control and omere maintenance.
DISEASE : Nijmegen breakage syndrome (NBS) [MIM:251260]: A disorder characterized by chromosomal instability, radiation sensitivity, microcephaly, growth retardation, immunodeficiency and predisposition to cancer, particularly to lymphoid malignancies. Note=The disease is caused by mutations affecting the gene represented in this entry.
Breast cancer (BC) [MIM:114480]: A common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type. Breast cancer is etiologically and genetically heterogeneous. Important genetic factors have been indicated by familial occurrence and bilateral involvement. Mutations at more than one locus can be involved in different families or even in the same case. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Aplastic anemia (AA) [MIM:609135]: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. It is characterized by peripheral pancytopenia and marrow hypoplasia. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.
Note=Defects in NBN might play a role in the pathogenesis of childhood acute lymphoblastic leukemia (ALL).
偶氮膦Ⅲ 號(hào):1914-99-4Similarity : Contains 1 BRCT domain.
Contains 1 FHA domain.
Database links : UniProtKB/Swiss-Prot: O60934.1
英文名稱  Anti-NRIP
中文名稱  雄激素受體復(fù)合物相關(guān)蛋白/核受體相互作用蛋白抗體
別    名  Androgen receptor complex associated protein; ARCAP; IQ motif and WD repeats 1; IQWD1v MSTP055; Nuclear receptor interaction protein; RP4 745I14.1; DCAF6_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
產(chǎn)品類型  一抗   
研究領(lǐng)域  腫瘤 心血管 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 
蛋白分子量  predicted molecular weight: 96kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NRIP
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
(石蠟切片需做抗原修復(fù))
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 

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