溴甲酚紫鈉號(hào)：62625-30-3   
英文名稱：BCP，Na；Bromocresol purole sodium salt；5',5''-Dibromo-o-cresolsulfonephthalein sodium salt    
其他名稱：溴甲酚紅鈉；5,5ˊ-二溴鄰甲酚磺酞鈉鹽；5,5′-二溴鄰甲酚紅鈉；5,5′-二溴鄰甲酚磺酰酞鈉   
號(hào)：62625-30-3    
C21H15Br2NaO5S=562.2   
級(jí)別：AR    
水溶性（1%,H2O）：合格   
pH變色域：5.2（黃）～6.8（紫）   
性狀(以下信息僅供參考)：黑褐色或紅棕色粉末，溶于水，熔點(diǎn)255 ℃   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)指示劑   
保存：RT 溴甲酚紫鈉號(hào)：62625-30-3儲(chǔ)存條件：
避光、干燥陰涼處封閉貯存,嚴(yán)禁與有毒、有害物品混放、混運(yùn)。本品為非危險(xiǎn) 產(chǎn)品可按一般化學(xué)品運(yùn)輸,輕搬動(dòng)輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運(yùn)輸條件比較苛刻。
運(yùn)輸：汽車運(yùn)輸、EMS郵政快遞，申通快遞等， 款到上海3天內(nèi)發(fā)貨； 
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存儲(chǔ)：應(yīng)貯存在干燥清潔避光的環(huán)境中，嚴(yán)禁與有毒物質(zhì)混放，以免污染（保質(zhì)期為兩年）。 
溴甲酚紫鈉號(hào)：62625-30-3主要優(yōu)級(jí)純、分級(jí)純和化學(xué)純3種：
（1）優(yōu)級(jí)純（GR：Guaranteed reagent），又稱一級(jí)品或保證試劑，99.8%，這種試劑純度Z高，雜質(zhì)含量Z低，適合于重要精密的分析工作和科學(xué)研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級(jí)試劑，純度很高，99.7%，略次于優(yōu)級(jí)純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學(xué)純（CP），又稱三級(jí)試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學(xué)校一般分析工作。使用藍(lán)色（深藍(lán)色）標(biāo)簽。
（4）實(shí)驗(yàn)試劑（LR：Laboratory reagent），又稱四級(jí)試劑。
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coupled receptor PGR14; GPR 154; gpr154; GPRA; MVTR; Neuropeptide S receptor 1; Neuropeptide S receptor; nps receptor; NPSR 1; NPSR; NPSR1; PGR 14; PGR14; PGR-14; Vasopressin receptor related receptor 1; VRR 1; VRR1; NPSR1_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
產(chǎn)品類型  一抗   
研究領(lǐng)域  細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號(hào) 
蛋白分子量  predicted molecular weight: 43kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NPSR1 (201-300aa)
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many 溴甲酚紫鈉號(hào)：62625-30-3different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR154 (G-protein coupled receptor 154), also known as NPSR1 (neuropeptide S receptor), GPRA (G-protein coupled receptor for asthma susceptibility) or PGR14, is a 371 amino acid protein that is thought to play a role in autocrine or paracrine signaling pathways. Ubiquitously expressed, GPR154 exists as nine alternatively spliced isoforms. Defects in the gene encoding GPR154 is the cause of asthma-related traits type 2 (ASRT2).
Function : Neuropeptide S receptor 1 (GPR154) is a receptor for Neuropeptide S. It is expressed on the epithelia of several organs including the intestine, and appears to be upregulated in inflammation. It is upregulated in macrophages after antigen challenge and is involved in the pathogenesis of asthma and other IgE-mediated diseases.
Subcellular Location : Cell Membrane and Cytoplasmic
Tissue Specificity : Ubiquitous. Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantly expressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, but not in control patients; whereas in epithelial cells, its expression is consistently stronger in asthma patients.
DISEASE : Defects in NPSR1 are a cause of asthma-related traits type 2 (ASRT2) [MIM:608584]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis.
Similarity : Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Database links : UniProtKB/Swiss-Prot: Q6W5P4.1
神經(jīng)肽S(neuropeptide S,NPS)是2002年發(fā)現(xiàn)的一種神經(jīng)肽,由20個(gè)氨基酸組成,通過(guò)激活其受體NPSR而發(fā)揮作用。NPS/NPSR系統(tǒng)參與調(diào)節(jié)覺(jué)醒和睡眠、焦慮、攝食、免疫等功能。神經(jīng)肽S（neuropeptide S，NPS），通過(guò)激活其同源受體（NPSR），并引發(fā)細(xì)胞內(nèi) Ca2+動(dòng)員，進(jìn)而調(diào)控失眠和憂慮，具有提高實(shí)驗(yàn)動(dòng)物的清醒程度以及有減少焦慮的作用。
英文名稱  Anti-NG/Neurogranin
中文名稱  神經(jīng)顆粒素抗體
別    名  Calmodulin binding protein; Hng; NEUG(55-78); NEUG_HUMAN; Neurogranin (protein kinase C substrate); Ng; NRGN; Protein kinase C substrate; RC3; BICKS.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit