Anti-KDM6B抗體,組蛋白去甲基化酶JMJD3抗體產(chǎn)品介紹：JMJD3 is a 1,679 amino acid nuclear protein that contains one JmjC domain and belongs to the highly conserved JmjC domain-containing protein family. Functioning as a histone demethylase, JMJD3 uses iron and ascorbate as cofactors to demethylate dimethylated and trimethylated Lys-27 residues of Histone H3, thereby playing an important role in the modification of the histone code. Additionally, JMJD3 regulates posterior development and is involved in the inflammatory response, specifically by mediating macrophage differentiation. JMJD3 is also thought to control the expression of neurogenesis-related proteins and, via this regulatory mechanism, may be necessary for neural commitment during early development. Two isoforms of JMJD3 exist due to alternative splicing events. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時(shí)4°C存儲(chǔ)，保質(zhì)期六個(gè)月，*存儲(chǔ)時(shí)建議分裝為10ul以上小包裝-20°C存儲(chǔ)，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-KDM6B抗體,組蛋白去甲基化酶JMJD3抗體

產(chǎn)品編號(hào) BYK-16894R

英文名稱 Anti-KDM6B
中文名稱 組蛋白去甲基化酶JMJD3抗體
別    名 Histone demethylase JMJD3; JmjC domain containing protein 3; JmjC domain-containing protein 3; Jumonji D3; Jumonji domain containing 3; Jumonji domain containing 3 histone lysine demethylase; Jumonji domain containing protein 3; Jumonji domain-containing protein 3; Kdm6b; KDM6B_HUMAN; KIAA0346; Lysine demethylase 6B; Lysine K specific demethylase 6B; Lysine specific demethylase 6B; Lysine-specific demethylase 6B.
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)      

抗體來(lái)源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)）

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