Anti-CREB-1抗體,環(huán)腺苷酸應(yīng)答元件結(jié)合蛋白抗體產(chǎn)品介紹：Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory. CREB knock out mice show diminished learning ability. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質(zhì)期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-CREB-1抗體,環(huán)腺苷酸應(yīng)答元件結(jié)合蛋白抗體

產(chǎn)品編號 BYK-0035R

英文名稱 CREB-1
中文名稱 環(huán)腺苷酸應(yīng)答元件結(jié)合蛋白抗體
別    名 Active transcription factor CREB; cAMP response element binding protein; cAMP responsive element binding protein 1; CREB1; CREB 1; CREB1; MGC9284; Transactivator protein; CREB; CREB1_HUMAN.
研究領(lǐng)域 免疫學(xué)  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子   

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請）

    Anti-CREB-1抗體,環(huán)腺苷酸應(yīng)答元件結(jié)合蛋白抗體更多優(yōu)質(zhì)產(chǎn)品有：

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溶質(zhì)攜帶物家族1抗體 Anti-SLC1A5
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腦特異性跨膜蛋白抗體 Anti-NETO2
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