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Anti-Claudin 14抗體,緊密連接蛋白14抗體供應商產(chǎn)品介紹:The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-14 is a multi-pass membrane protein that is expressed in liver, kidney and ear. Defects in the gene encoding claudin-14 are the cause of non-syndromic sensorineural deafness autosomal recessive type 29 (DFNB29), a form of hearing loss resulting from damage to either nerve pathways or neural receptors of the inner ear.
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保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲,保質(zhì)期六個月,*存儲時建議分裝為10ul以上小包裝-20°C存儲,并避免反復凍融,保質(zhì)期一年。
產(chǎn)品名稱 Anti-Claudin 14抗體,緊密連接蛋白14抗體供應商
產(chǎn)品編號 BYK-10554R
英文名稱 Claudin 14
中文名稱 緊密連接蛋白14抗體
別 名 Claudin-14; CLDN14; DFNB29; Human CLDN14 gene; OTTHUMP00000109046; OTTHUMP00000109049; OTTMUSP00000021531; UNQ777/PRO1571.
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
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