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產(chǎn)品介紹:
【產(chǎn)品名稱】:誘捕受體3抗體,Anti-DcR3/TR6抗體
【產(chǎn)品類型】:一抗
【產(chǎn)品編號】:BYk-1716R
【相關(guān)標(biāo)記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 狀】: Lyophilized or Liquid
【濃 度】: 1mg/1ml
【亞 型】: IgG
【規(guī) 格】:0.1ml/100ug,0.2ml/200ug
【抗體來源】: Rabbit OR MOUSE
【克隆類型】: polyclonal or monoclonal
【產(chǎn)品用途】:科研實驗,用于免疫組化實驗,WB實驗、IF、IP、ELISA實驗,相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,F(xiàn)ITC標(biāo)記,BIO等。
【貯 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【信息詳情】: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.
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