周期素依赖性激酶4抗体，Anti-CDK4抗体 返回列表页

“周期素依赖性激酶4抗体，Anti-CDK4抗体”应用于IHC、WB、 IF、IP、ELISA，质量保证，无效免费退换，另外本公司生产经营各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂，咨询！

产品介绍：

【产品名称】：周期素依赖性激酶4抗体，Anti-CDK4抗体

【产品类型】：一抗

【产品编号】：BYk-0633R                    

【相关标记】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 状】： Lyophilized or Liquid

【浓 度】： 1mg/1ml

【亚 型】： IgG

【规 格】：0.1ml/100ug，0.2ml/200ug

【抗体来源】： Rabbit OR MOUSE

【克隆类型】： polyclonal or monoclonal

【产品用途】：科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。

【贮 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【详细介绍】： CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16（INK4a）. This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product （Rb）. Mutations in this gene as well as in its related proteins including D-type cyclins, p16（INK4a） and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
 

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