Anti-phospho-BAD(pSer128)抗體,磷酸化相關(guān)死亡促進(jìn)因子抗體產(chǎn)品詳細(xì)資料

產(chǎn)品編號(hào) BYK-0893R

英文名稱 phospho-BAD (Ser128)
中文名稱 磷酸化相關(guān)死亡促進(jìn)因子抗體
別    名 Bad (phospho S128); Bad (phospho Ser128); p-Bad (S128);p- Bad (Ser128); p-Bad (phospho Ser128); BBC 2; BBC2; BBC6; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6.
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  新陳代謝  
分 子 量 22kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 

抗體來(lái)源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應(yīng)用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應(yīng)用不做依據(jù)，具體產(chǎn)品應(yīng)用與實(shí)驗(yàn)稀釋比請(qǐng)！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-phospho-BAD(pSer128)抗體,磷酸化相關(guān)死亡促進(jìn)因子抗體產(chǎn)品介紹 

      Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform. 

 此相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記 

     Anti-phospho-BAD(pSer128)抗體,磷酸化相關(guān)死亡促進(jìn)因子抗體相關(guān)產(chǎn)品：

     Anti-FGL2抗體,*原酶/維介素抗體

Anti-Forchlorfenuron抗體,氯吡脲抗體
Anti-FAM174B抗體,FAM174B蛋白抗體
Anti-FCER1A抗體,FC段IgE受體α多肽抗體
Anti-FDFT1抗體,法尼基二磷酸法尼基轉(zhuǎn)移酶1/鯊烯合成酶抗體
Anti-FOXP4抗體,叉頭蛋白P4抗體
Anti-FMDV 3ABC抗體,口蹄疫病毒3ABC抗體
Anti-FBXL20抗體,FBXL20蛋白抗體
Anti-Fibronectin/Ugl-Y3抗體,纖維連接蛋白/Ugl-Y3抗體
Anti-FABP6抗體,回腸脂肪酸結(jié)合蛋白抗體
Anti-FPR1抗體,甲酸基肽受體1抗體
Anti-FGFR1抗體,堿性成纖維細(xì)胞生長(zhǎng)因子受體1抗體
Anti-GLUT1抗體,葡萄糖轉(zhuǎn)運(yùn)蛋白1抗體
Anti-GLUT2抗體,葡萄糖轉(zhuǎn)運(yùn)蛋白2抗體
Anti-Cobra poison Protein抗體,眼鏡蛇蛇毒蛋白抗體
Anti-GNB1抗體,G蛋白/鳥苷酸結(jié)合蛋白抗體
Anti-GABA A Receptor alpha 1抗體,G1氨基丁酸A型受體α1抗體
Anti-GAD65抗體,*脫羧酶65抗體
Anti-Galanin抗體,甘丙肽/神經(jīng)節(jié)肽抗體
Anti-Galectin 3抗體,半乳糖凝集素3抗體
Anti-GAP43抗體,神經(jīng)生長(zhǎng)相關(guān)蛋白43
Anti-GAPDH抗體,3-磷酸甘油醛脫氫酶抗體
Anti-GFRA4抗體,GDNF家族受體α4抗體 GDNFRα4