抗體名稱:Anti-beta-Amyloid 1-42(CT),β淀粉樣肽1-42(C端)/β-Amyloid 1-42(CT)抗體
產(chǎn)品編號(hào):BYK-0076M
產(chǎn)品別名:beta Amyloid(1-42); beta Amyloid 1-42; beta-Amyloid 1-42; Amyloid 1-42; A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid Beta A4 Protein Precursor; Amyloid Beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; Beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; A4_HUMAN.
相關(guān)標(biāo)記一抗: FITC HRP Biotin RBITC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Cy3 Cy5 Cy5.5 Cy7 Gold PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 .
濃 度: 1mg/1ml
抗體來源(宿主):兔源、鼠源、其他
克 ?。?jiǎn)慰寺】贵w、多克隆抗體
抗 體 類 型:一抗
性 狀: 凍干粉或液體
儲(chǔ)存液: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 or PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
產(chǎn)品應(yīng)用 Immunohistochemistry (IHC), Flow Cytometry (FACS) , Western Blotting (WB) , ELISA , Immunohistochemistry , Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) , Immunoprecipitation (IP) , Immunocytochemistry (ICC) ,Immunofluorescence (IF)等。(咨詢,點(diǎn)擊查看)
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Anti-beta-Amyloid 1-42(CT),β淀粉樣肽1-42(C端)/β-Amyloid 1-42(CT)抗體抗體依據(jù)重鏈抗原性的不同分為五類:IgG、IgA、IgM、IgD、IgE。
各類抗體Anti-GRP促胃泌素釋放肽抗體主要功能有:
(1)IgG :血清中含量zui高,因此是zui重要的抗感染分子,包括抗菌、抗病毒、抗毒素等。 IgG 還能激活補(bǔ)體,結(jié)合并增強(qiáng)巨噬細(xì)胞的吞噬功能(調(diào)理作用和 ADCC 效應(yīng)),穿過胎盤,保護(hù)胎兒及新生嬰兒免受感染。
(2)IgA :分單體和雙體兩種。前者存在血清中,后者存在于黏膜表面及分泌液中,是黏膜局部抗感染的重要因素。
(3)IgM :是分子量zui大,體內(nèi)受感染后zui早產(chǎn)生的抗體,具有很強(qiáng)的激活補(bǔ)體和調(diào)理作用,因此是重要的抗感染因子,且常用于診斷早期感染?!?/span>
(4)IgD :主要存在于成熟 B 細(xì)胞表面,是 B 細(xì)胞識(shí)別抗原的受體。
(5)IgE :血清中含量zui少的抗體,某些過敏性體質(zhì)的人血清中可檢測(cè)到,參與介導(dǎo) I 型超敏反應(yīng)和抗寄生蟲感染。
相關(guān)知識(shí):
抗原修復(fù)——原因 *常規(guī)的石蠟切片標(biāo)本均用甲醛固定,結(jié)果使得: -抗原性物質(zhì)形成醛鍵、羧甲鍵而被封閉了部分抗原決定簇; -蛋白之間發(fā)生交聯(lián)而使抗原決定簇隱蔽。 *要求:在染色時(shí),需要*行抗原修復(fù)或暴露,即將固定時(shí)分子之間所形成的交聯(lián)破壞,而恢復(fù)抗原的原有空間形態(tài)抗原修復(fù)——方法 *化學(xué)方法 *加熱方法 -水浴加熱法 -微波照射法 -高壓加熱法 -酸水解法。
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