“B Raf抗体，Anti-B-Raf抗体”应用于IHC、WB、 IF、IP、ELISA，质量保证，无效免费退换，另外本公司生产经营各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂，咨询！
产品介绍：
【产品名称】：B Raf抗体，Anti-B-Raf抗体
【产品类型】：一抗
【产品编号】：BYk-1089R
【相关标记】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 状】： Lyophilized or Liquid
【浓 度】： 1mg/1ml
【亚 型】： IgG
【规 格】：0.1ml/100ug，0.2ml/200ug
【抗体来源】： Rabbit OR MOUSE
【克隆类型】： polyclonal or monoclonal
【产品用途】：科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
【贮 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【详细介绍】：The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK （also known as MAP kinase kinase）. Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
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