背景介紹:This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined.
別名:DFNB3; MYO15; MYO15_HUMAN; MYO15A; Myosin XV; Myosin XVA; Unconventional myosin 15; Unconventional myosin XV; Unconventional myosin-15; Unconventional myosin-XV.
肌球蛋白15A抗體,Anti-MYO15A抗體簡(jiǎn)單介紹:
產(chǎn)品編號(hào):BYK-19154R
英文名稱:Anti-MYO15A
中文名稱:肌球蛋白15A抗體
產(chǎn)品規(guī)格:50ul;100ul;200ul;1ml,*
抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
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性 狀 Lyophilized or Liquid
濃 度 1mg/ml
肌球蛋白15A抗體,Anti-MYO15A抗體產(chǎn)品信息:
博研生物小課堂:
常用激光器對(duì)應(yīng)熒光素的選擇:
藍(lán)色激光器熒光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
紅色激光器熒光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黃色激光器熒光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
1.陽性細(xì)胞染色分布有三種類型:細(xì)胞漿、細(xì)胞核、細(xì)胞膜表面。大部分抗原見于細(xì)胞漿,可見于整個(gè)胞漿或部分胞漿
2.陽性細(xì)胞分布可分為灶型和彌漫性
3.由于細(xì)胞內(nèi)含抗原量不同,所以染色強(qiáng)度不一。如果細(xì)胞之間染色強(qiáng)度相同,常提示其反應(yīng)為非特異性
4.陽性細(xì)胞染色定位于單個(gè)細(xì)胞,且與陰性細(xì)胞相互交雜分布;而非特異性染色常不限于單個(gè)細(xì)胞,而是累及一片細(xì)胞。
5.切片邊緣、刀痕或褶皺區(qū)域,壞死或擠壓的細(xì)胞區(qū),膠原結(jié)締組織等,常表現(xiàn)為相同的陽性染色強(qiáng)度,不能用于判斷陽性。
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