EDTA抗原修復(fù)液(50X,pH8)使用說明書*,*,庫存現(xiàn)貨,無效果,免費(fèi)退款。公司現(xiàn)貨銷售,量大折扣,咨詢。詳細(xì)信息如下。
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EDTA抗原修復(fù)液(50X,pH8)使用說明書分子生物學(xué)領(lǐng)域:
涉及核酸純化、常用分子生物學(xué)試劑、PCR等相關(guān)試劑盒。
分子生物學(xué)試劑:擁有的價(jià)格優(yōu)勢(shì),品質(zhì)可信賴,市場(chǎng)占比龐大。
產(chǎn)品名稱 | 英文名稱 | 包裝 |
EDTA抗原修復(fù)液(50X,pH8)使用說明書 | EDTA Antigen Retrieval Solution(50X,pH8) | 可根據(jù)客戶要求訂制 |
EDTA抗原修復(fù)液(50X,pH8)使用說明書收貨注意事項(xiàng):
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Subunit : Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR (By similarity). This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with SPAG9 and GADD45A. Interacts with CDC25B, CDC25C, DUSP1, DUSP10, DUSP16, NP60, FAM48A and TAB1. Interacts with casein kinase II subunits CSNK2A1 and CSNK2B.
Subcellular Location : Cytoplasm. Nucleus.
Tissue Specificity : Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney.
Post-translational modifications : Dually phosphorylated on Thr-180 and Tyr-182 by the MAP2Ks MAP2K3/MKK3, MAP2K4/MKK4 and MAP2K6/MKK6 in response to inflammatory citokines, environmental stress or growth factors, which a ctivates the enzyme. Dual phosphorylation can also be mediated by TAB1-mediated autophosphorylation. TCR engagement in T-cells also leads to Tyr-323 phosphorylation by ZAP70. Dephosphorylated and inactivated by DUPS1, DUSP10 and DUSP16.
Acetylated at Lys-53 and Lys-152 by KAT2B and EP300. Acetylation at Lys-53 increases the affinity for ATP and enhances kinase activity. Lys-53 and Lys-152 are deacetylated by HDAC3.
Ubiquitinated. Ubiquitination leads to degradation by the proteasome pathway.
Similarity : Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Contains 1 protein kinase domain.
Database links :
UniProtKB/Swiss-Prot: Q16539.3
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