堿性品紅號(hào)：632-99-5
英文名稱：Fuchsin basic；Basic Violet 14；Magenta；Basic magenta；Basic rubin；C.I. 42510
其他名稱：堿性復(fù)紅；品紅；鹽基品紅；堿性紫14；玫苯胺；洋紅；深紅色；紅色苯胺染料；堿性新品紅；玫瑰苯胺鹽酸鹽；(4-(4-氨基苯基)(4-亞氨基環(huán)己-2,5-二烯亞基)甲基)-2-甲基本胺鹽酸鹽；玫瑰色素；4-胺-3-甲苯雙(4-胺苯)甲醇
號(hào)：632-99-5
C20H20N3Cl=337.85
級(jí)別：IND
干燥失重：≤14.6%
亞硫酸鈉試驗(yàn)：合格
灼燒殘?jiān)?le;0.2%
性狀(以下信息僅供參考)：綠色或黃綠色金屬光澤結(jié)晶，為品紅和副品紅(PArArosAnilinE)鹽酸鹽或乙酸鹽的混合物。200℃以上分解。溶于乙醇和戊醇，微溶于水，不溶于乙迷。溶于酒精呈紅色；溶于熱水呈紅紫色，遇濃硫酸呈黃棕色，稀釋后幾乎無(wú)色；水溶液加氫氧化鈉液呈帶有紅色沉淀的幾乎無(wú)色的液體。Z大吸收波長(zhǎng)(乙醇中)543nm(ε93000)。有毒
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)用于配制席夫試劑檢測(cè)醛類，用于萃取光度法測(cè)定某些酸根離子及金屬離子。也用于光度法檢測(cè)溴，亞硝酸鹽和二氧化硫。用作極譜分析中的*抑制劑。還用作生化分析的核染料,為Z強(qiáng)的核染料。能使粘朊、彈性組織和嗜品紅的顆粒染色。中樞神經(jīng)的核染色；細(xì)菌學(xué)中用以鑒別結(jié)核桿菌；分析化學(xué)中配制席夫試劑檢驗(yàn)醛類。用溴酸鹽滴定的氧化還原指示劑
保存：RT
堿性品紅號(hào)：632-99-5儲(chǔ)存條件：
避光、干燥陰涼處封閉貯存,嚴(yán)禁與有毒、有害物品混放、混運(yùn)。本品為非危險(xiǎn) 產(chǎn)品可按一般化學(xué)品運(yùn)輸,輕搬動(dòng)輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運(yùn)輸條件比較苛刻。
運(yùn)輸：汽車運(yùn)輸、EMS郵政快遞，申通快遞等， 款到上海3天內(nèi)發(fā)貨；
售后：如您對(duì)我們的產(chǎn)品服務(wù)及技術(shù)指標(biāo)有特殊要求，請(qǐng)及時(shí)通知我方。
存儲(chǔ)：應(yīng)貯存在干燥清潔避光的環(huán)境中，嚴(yán)禁與有毒物質(zhì)混放，以免污染（保質(zhì)期為兩年）。
堿性品紅號(hào)：632-99-5主要優(yōu)級(jí)純、分級(jí)純和化學(xué)純3種：
（1）優(yōu)級(jí)純（GR：Guaranteed reagent），又稱一級(jí)品或保證試劑，99.8%，這種試劑純度Z高，雜質(zhì)含量Z低，適合于重要精密的分析工作和科學(xué)研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級(jí)試劑，純度很高，99.7%，略次于優(yōu)級(jí)純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學(xué)純（CP），又稱三級(jí)試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學(xué)校一般分析堿性品紅號(hào)：632-99-5When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Non-T cell activation linker (NTAL), a transmembrane adaptor protein, is also designated membrane-associated adapter molecule, Williams-Beuren syndrome chromosome region 15 protein or LAB (linker of activated B cells). NTAL is present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells, and in monocytes and mast cells, but not in resting T lymphocytes. NTAL becomes rapidly tyrosine-phosphorylated upon cross-linking of the B cell receptor (BCR) or of high-affinity Fc g and Fc e receptors of myeloid cells and then associates with the cytoplasmic signaling molecules. NTAL is highly expressed in spleen, lymph node germinal centers and peripheral blood lymphocytes. Defects in the gene encoding for NTAL may cause the musculo-skeletal and cardio-vascular abnormalities that characterize the rare developmental disorder Williams-Beuren syndrome (WBS).
Function : Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Subunit : When phosphorylated, interacts with GRB2. May also interact with SOS1, GAB1 and CBL.
Subcellular Location : Cell membrane. Present in lipid rafts.
Tissue Specificity : Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level).
Post-translational modifications : Phosphorylated on tyrosines following cross-linking of BCR in B-cells, FCGR1 in myeloid cells, or FCER1 in mast cells; which induces the recruitment of GRB2.
May be polyubiquitinated.
DISEASE : Note=LAT2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal
